• Click Here If You Need Help Right Now

LipidRescue™ Resuscitation

20% lipid emulsion for rescue from drug toxicity
  • Click Here If You Need Help Right Now

IN AN EMERGENCY:
  • Click Here If You Need Help Right Now
  • Welcome
  • Background
  • Treatment Overview
  • Medical Literature
    • Case Reports
      • Local Anesthetic Toxicity - Adult
      • Local Anesthetic Toxicity -Pediatric
      • Non-Local Anesthetic Toxicity
      • Veterinary
    • Laboratory Studies
      • Local Anesthetic Toxicity
      • Non-Local Anesthetic Toxicity
      • Mechanisms
    • Clinical Studies
    • Reviews
    • Surveys and Registries
    • Editorials
    • Guidelines and Recommendations
    • Miscellaneous
  • Local Anesthetic Toxicity
    • Overview
    • Epidemiology
  • Post Your Cases
  • LipidRescue for Your Facility
  • Instructions (PDFs)
  • Sample LipidRescue™ Kit
  • LipidRescue™ Experiments (Videos)
  • Weinberg Bio
  • Registry Proposal
  • Ask Us
  • An important request for all LipidRescuers
  • Professional Connections
    Places of interest
    • University of Illinois at Chicago Department of Anesthesiology
      This has been my professional home for 20 years.
    • The Journal of Anesthesiology
    • NYSORA: The NY School of Regional Anesthesia
    • The American Society of Regional Anesthesia
    • Regional Anesthesia and Pain Medicine
      The official publication of ASRA
  • Contact Us
  • Legal Disclaimer
  • Login
Powered by Squarespace
A Review of Lipid Resuscitation
  • A Comprehensive Review of Lipid Resuscitation
  • Research (Bupivacaine Cardiac Preservation)
  • Editorials

    • Tucker GT. Physiologically based pharmacokinetic-pharmacodynamic modeling to the rescue: understanding how resuscitation from local anesthetic overdose with lipid emulsions works. Anesthesiology. 2014 Apr;120(4):795-6.
    • Zausig YA, Zink W, Graf BM. Lipophilicity of local anesthetics and success of lipid emulsion therapy. Crit Care Med. 2012 Jan;40(1):359-60.
    • Killoran PV, Cattano D. From bedside to bench and back: perfecting lipid emulsion therapy for local anesthetic toxicity. Anesthesiology. 2011 Dec;115(6):1151-2.
    • Weinberg G, Rubinstein I. Pig in a Poke: Species Specificity in Modeling Lipid Resuscitation. Anesth Analg. 2011 Dec 20. [Epub ahead of print]
    • Kawaraguchi Y, Roth DM, Patel HH. From Local to Global: Intralipid Makes a Move. Anesthesiology. 2011 Jun 8. [Epub ahead of print]
    • Uncles DR, et al. Local anaesthetic systemic toxicity treated with intravenous lipid emulsion: ineffective treatment or selection of an inadequate lipid rescue dose? Eur J Anaesthesiol. 2011 May;28(5):390-1.
    • Weinberg GL. Intravenous lipid emulsion: why wait to save a life? Emerg Med Australas. 2011 Apr;23(2):113-5.
    • Cave G, Harvey M. Intravenous lipid emulsion as antidote: How should we chew the fat in 2011? Crit Care Med 2011 Apr; 39(4): 919-20.
    • Murray DB, Bateman DN.Use of intravenous lipids. Not yet in all overdoses with failed resuscitation. BMJ. 2011 Apr 8;342:d2265.
    • Samuels TL, et al. Logging the potential for intravenous lipid emulsion in propranolol and other lipophilic drug overdoses. Anaesthesia. 2011 Mar;66(3):221-2.
    • Davis W. Factors related to recovery in a cat treated for lidocaine intoxication. J Am Vet Med Assoc. 2011 Feb 1;238(3):284; author reply 284.
    • Weinberg G, et al. Partitioning effect in lipid resuscitation: further evidence for the lipid sink. Crit Care Med. 2010 Nov;38(11):2268-9.
    • Woehlck HJ, El-Orbany M. Anesthetic effects and lipid resuscitation protocols. Anesthesiology. 2010 Feb;112(2):499-500
    • McKevith J, Banks A. Lipid resuscitation. Resuscitation. 2009 Dec;80(12):1448. Epub 2009 Oct 4.
    • Isherwood P. Lipid rescue: small trials and animal research. Anaesthesia. 2009 Dec;64(12):1380
    • Cave G, Harvey M. Intravenous lipid emulsion as antidote beyond local anesthetic toxicity: a systematic review. Anesthesiology. 2009 Sep;111(3):498-505.
    • Picard J, Harrop-Griffiths W. Lipid emulsion to treat drug overdose: past, present and future. Anaesthesia. 2009 Feb;64(2):119-21.
    • Picard J, Ward S, Meek T. Antidotes to anesthetic catastrophe: lipid emulsion and dantrolene. Anesth Analg. 2007 Jul;105(1):283-4
    • Brull SJ. Lipid emulsion for the treatment of local anesthetic toxicity: patient safety implications. Anesth Analg. 2008 May;106(5):1337-9
    • Rowlingson JC. Lipid rescue: a step forward in patient safety? Likely so! Anesth Analg. 2008 May;106(5):1333-6
    • Weinberg GL. Lipid infusion therapy: translation to clinical practice. Anesth Analg. 2008 May;106(5):1340-2
    • Picard J, Meek T. Lipid emulsion to treat overdose of local anaesthetic: the gift of the glob. Anaesthesia 2006;61:107-9.
    • Weinberg G. Lipid infusion resuscitation for local anesthetic toxicity: proof of clinical efficacy. Anesthesiology 2006;105:7-8.
    • Groban L, Butterworth J. Lipid reversal of bupivacaine toxicity: has the silver bullet been identified? Reg Anesth Pain Med 2003;28:167-9.
Copyright © 2012, Guy Weinberg, MD. All rights reserved.