Newer LipidRescue Experiments Comparing Lipid with Saline and "No-Treatment'
This is a group of three experiments on anesthetized rats. Each recieves a large bolus of bupivacaine, then in addition to ventilation with 100% oxygen and chest compressions are given one of three iv treatments: nothing, saline or lipid emulsion.
There is minimal recovery of hemodynamics over several minutes of resuscitation. This is a 'no-treatment' control. Note the audio commentary.
This experiment controls for the effects of volume on recovery from bupivacaine overdose. There is minimal hemodynamic recovery.
This subject received lipid emulsion in addition to chest compressions and ventilation with 100% oxygen. Recovery is complete by four minutes. Note the audio commentary.