LipidRescue™ Resuscitation

Case Reports: Non-Local Anesthetic Toxicity

• Muller SH, Diaz JH, Kaye AD. Intralipid Emulsion Rescue Therapy: Emerging Therapeutic Indications in Medical Practice. J La State Med Soc. 2016 May-Jun;168(3):101-3.
• Avcil M, et al. Simultaneous Use of Intravenous Lipid Emulsion and Plasma Exchange Therapies in Multiple Drug Toxicity. Med Princ Pract. 2016;25(6):577-579. Epub 2016 Aug 22.
• Ten Broeke R, et al. Early treatment with intravenous lipid emulsion in a potentially lethal hydroxychloroquine intoxication. Neth J Med. 2016 Jun;74(5):210-4.
• Muraro L, et al. Intralipid in acute caffeine intoxication: a case report. J Anesth. 2016 Oct;30(5):895-9.
• Thompson AM, et al. Intravenous lipid emulsion and high-dose insulin as adjunctive therapy for propranolol toxicity in a pediatric patient. Am J Health Syst Pharm. 2016 Jun 15;73(12):880-5.
• Besserer F, et al. Tilmicosin toxicity: a case of accidental human tilmicosin injection managed with calcium, high-dose insulin and intravenous lipid emulsion therapy. Clin Toxicol (Phila). 2016 Sep;54(8):812-3
• Tse J, et al. The use of intravenous lipid emulsion therapy in acute methamphetamine toxicity. Am J Emerg Med. 2016 Aug;34(8):1732.e3-4. doi: 10.1016/j.ajem.2015.12.055. Epub 2015 Dec 19.
• Bayram B, et al. Successful Treatment of Propafenone Intoxication With Intravenous Lipid Emulsion. Pharmacotherapy. 2015 Oct;35(10):e149-52.
• Westrol MS, et al. Use of an Intravascular Heat Exchange Catheter and Intravenous Lipid Emulsion for Hypothermic Cardiac Arrest After Cyclobenzaprine Overdose. Ther Hypothermia Temp Manag. 2015 Sep;5(3):171-6.
• Mukhtar O, et al. Lesson of the month 1: Acute flecainide overdose and the potential utility of lipid emulsion therapy. Clin Med (Lond). 2015 Jun;15(3):301-3.
• Escajeda JT, et al. Successful treatment of metoprolol-induced cardiac arrest with high-dose insulin, lipid emulsion, and ECMO. Am J Emerg Med. 2015 Aug;33(8):1111.e1-4.
• Abdi A, et al. Diphenhydramine overdose with intraventricular conduction delay treated with hypertonic sodium bicarbonate and i.v. lipid emulsion. West J Emerg Med. 2014 Nov;15(7):855-8.
• Rodríguez B, et al. Lipid emulsion use precluding renal replacement therapy. J Emerg Med. 2014 Dec;47(6):635-7.
• Meaney CJ, et al. Intravenous lipid emulsion in the management of amlodipine overdose. Hosp Pharm. 2013 Nov;48(10):848-54.
• Agarwala R, et al. Prolonged use of intravenous lipid emulsion in a severe tricyclic antidepressant overdose. J Med Toxicol. 2014 Jun;10(2):210-4.
• Punja M, Caution with interpreting laboratory results after lipid rescue therapy. Am J Emerg Med. 2013 Oct;31(10):1536.e1-2.
• Bartos M, Knudsen K. Use of intravenous lipid emulsion in the resuscitation of a patient with cardiovascular collapse after a severe overdose of quetiapine. Clin Toxicol (Phila). 2013 Jul;51(6):501-4.
• Arslan ED, et al. Treatment of quetiapine overdose with intravenous lipid emulsion. Keio J Med. 2013;62(2):53-7. Epub 2013 May 27.
• Monteiro N, et al. Severe diltiazem poisoning treated with hyperinsulinaemia-euglycaemia and lipid emulsion. Case Rep Crit Care. 2013;2013:138959.
• Arora NP, et al. Usefulness of intravenous lipid emulsion for cardiac toxicity from cocaine overdose. Am J Cardiol. 2013 Feb 1;111(3):445-7.
• Harvey M, Cave G.Case report: successful lipid resuscitation in multi-drug overdose with predominant tricyclic antidepressant toxidrome. Int J Emerg Med. 2012 Feb 2;5(1):8. [Epub ahead of print]
• Blaber MS, et al. "Lipid Rescue" for Tricyclic Antidepressant Cardiotoxicity. Emerg Med. 2012 Jan 11. [Epub ahead of print]
• Jakkala-Saibaba R, et al. Treatment of cocaine overdose with lipid emulsion. Anaesthesia. 2011 Dec;66(12):1168-70.
• Liang CW, Diamond SJ, Hagg DS. Lipid rescue of massive verapamil overdose: a case report. J Med Case Reports. 2011 Aug 20;5(1):399
• Jovic-Stosic J, et al. Severe propranolol and ethanol overdose with wide complex tachycardia treated with intravenous lipid emulsion: a case report. Clin Toxicol (Phila). 2011 Jun;49(5):426-30.
• McAllister RK, Tutt CD, Colvin CS. Lipid 20% emulsion ameliorates the symptoms of olanzapine toxicity in a 4-year-old. Am J Emerg Med. 2011 Jun 2. [Epub ahead of print]
• Castanares-Zapatero D, et al. Lipid Emulsion as Rescue Therapy in Lamotrigine Overdose. J Emerg Med. 2011 May 26.
• French D, et al. Serum verapamil concentrations before and after Intralipid® therapy during treatment of an overdose.Clin Toxicol (Phila). 2011 Apr;49(4):340-4.
• Boegevig S, et al. Successful reversal of life threatening cardiac effect following dosulepin overdose using intravenous lipid emulsion. Clin Toxicol (Phila). 2011 Apr;49(4):337-9.
• Montiel V, Gougnard T, Hantson P. Diltiazem poisoning treated with hyperinsulinemic euglycemia therapy and intravenous lipid emulsion. Eur J Emerg Med. 2011 Apr;18(2):121-3.
• Franxman TJ, Al-Nabhan M, Cavallazzi RS, Speak AJ.Lipid emulsion therapy for verapamil overdose. Ann Intern Med. 2011 Feb 15;154(4):292.
• Stellpflug SJ, et al. Intentional overdose with cardiac arrest treated with intravenous fat emulsion and high-dose insulin. Clin Toxicol (Phila). 2010 Mar;48(3):227-9.
• Young AC, Velez LI, Kleinschmidt KC.Intravenous fat emulsion therapy for intentional sustained-release verapamil overdose. Resuscitation. 2009 May;80(5):591-3. Epub 2009 Mar 17.
• Weinberg G, et al. Reversal of haloperidol-induced cardiac arrest by using lipid emulsion. Ann Intern Med. 2009 May 19;150(10):737-8.
• Finn SD, et al. Early treatment of a quetiapine and sertraline overdose with Intralipid.Anaesthesia. 2009 Feb;64(2):191-4
• Sirianni AJ, et al. Use of Lipid Emulsion in the Resuscitation of a Patient With Prolonged Cardiovascular Collapse After Overdose of Bupropion and Lamotrigine. Ann Emerg Med. 2008 Apr;51(4):412-5, 415.e1