LipidRescue™ Resuscitation

Pt 65y;68kg;hipotiroidism;elective surgery for wrist fracture. We performed an axillary plexus block US-guided with 35mL of local anesthetic solution (lidocaine 1% + ropivacaine 0,375%). Aspiration was negative every time of inyection. No inmediate complications were noted. After 25 minutes the pt presented a seizure episode that lasted 2 minutes, remaining unresponsive after the event. Oxygen support was given by facemask. Vitals signs were stable. Infussion with Intralipid 20% was started inmediately; an initial bolus of 1,5mL/kg followed by a continuous infussion of 0,25mL/kg/hour for 2 hours. After 10 minutes of beginning administration, pt was fully recovered. Surgery was performed with no complications. Pt follow-up for 6 months did not revealed any significant finding.

Hello!
Thank you for posting. We just had to perform lipid rescusitation on a patient who received local anesthetic for a hemorrhoidectomy. A difficulty we found was programing the pump for the recommended .25ml/kg/min. The pump would have needed to be set at approximately 1040 ml/hour. That exceeded our pumps limits.I see that you stated your patient received a continuous infussion of 0.25ml/kg/HOUR. That would make the infusion easier on the patient (through the PIV), and programing of pumps. Do you know of any research that proves the pump can be set at the 0.25ml/kg/hour?
Thank you,
Amanda Regan