Click Here If You Need Help Right Now
LipidRescue™ Resuscitation
20% lipid emulsion for rescue from drug toxicity
Click Here If You Need Help Right Now
IN AN EMERGENCY:
Click Here If You Need Help Right Now
Welcome
Background
Treatment Overview
Medical Literature
Case Reports
Local Anesthetic Toxicity - Adult
Local Anesthetic Toxicity -Pediatric
Non-Local Anesthetic Toxicity
Veterinary
Laboratory Studies
Local Anesthetic Toxicity
Non-Local Anesthetic Toxicity
Mechanisms
Clinical Studies
Reviews
Surveys and Registries
Editorials
Guidelines and Recommendations
Miscellaneous
Local Anesthetic Toxicity
Overview
Epidemiology
Post Your Cases
LipidRescue for Your Facility
Instructions (PDFs)
Sample LipidRescue™ Kit
LipidRescue™ Experiments (Videos)
Weinberg Bio
Registry Proposal
Ask Us
An important request for all LipidRescuers
Professional Connections
Places of interest
University of Illinois at Chicago Department of Anesthesiology
This has been my professional home for 20 years.
The Journal of Anesthesiology
NYSORA: The NY School of Regional Anesthesia
The American Society of Regional Anesthesia
Regional Anesthesia and Pain Medicine
The official publication of ASRA
Login
Contact Us
Legal Disclaimer
A Review of Lipid Resuscitation
A Comprehensive Review of Lipid Resuscitation
Research (Bupivacaine Cardiac Preservation)
Reviews
Muller SH, Diaz JH, Kaye AD. Intralipid Emulsion Rescue Therapy: Emerging Therapeutic Indications in Medical Practice. J La State Med Soc. 2016 May-Jun;168(3):101-3.
Hayes BD, et al. Systematic review of clinical adverse events reported after acute intravenous lipid emulsion administration. Clin Toxicol (Phila). 2016 Jun;54(5):365-404.
Hoegberg LC, et al. Systematic review of the effect of intravenous lipid emulsion therapy for local anesthetic toxicity. Clin Toxicol (Phila). 2016 Mar;54(3):167-93
Levine M, et al. Lipid Emulsion Workgroup. Systematic review of the effect of intravenous lipid emulsion therapy for non-local anesthetics toxicity. Clin Toxicol (Phila). 2016 Mar;54(3):194-221.
Grunbaum AM, et al. Review of the effect of intravenous lipid emulsion on laboratory analyses. Clin Toxicol (Phila). 2016;54(2):92-102. doi: 10.3109/15563650.2015.1115515. Epub 2015 Dec 1.
Vasques F, et al. A Review of Local Anesthetic Systemic Toxicity Cases Since Publication of the American Society of Regional Anesthesia Recommendations: To Whom It May Concern. Reg Anesth Pain Med. 2015 Nov-Dec;40(6):698-705.
Collins S, et al. Lipid Emulsion in Treatment of Local Anesthetic Toxicity. J Perianesth Nurs. 2015 Aug;30(4):308-20.
Fettiplace MR, et al. Past, Present, and Future of Lipid Resuscitation Therapy. JPEN J Parenter Enteral Nutr. 2015 Sep;39(1 Suppl):72S-83S.
Damitz R, Chauhan A. Parenteral emulsions and liposomes to treat drug overdose. Adv Drug Deliv Rev. 2015 Aug 1;90:12-23.
Gosselin S, et al. Methodology for AACT evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning. Clin Toxicol (Phila). 2015 Jul;53(6):557-64.
Muller SH, Diaz JH, Kaye AD. Clinical applications of intravenous lipid emulsion therapy. J Anesth. 2015 Dec;29(6):920-6.
Cao D, et al. Intravenous lipid emulsion in the emergency department: a systematic review of recent literature. J Emerg Med. 2015 Mar;48(3):387-97.
Dickerson DM, Apfelbaum JL. Local anesthetic systemic toxicity. Aesthet Surg J. 2014 Sep;34(7):1111-9.
Nouette-Gaulain K, et al. [Intravenous lipid emulsion and local anesthetic-induced systemic toxicity: mechanisms and limits] [Article in French] Ann Fr Anesth Reanim. 2014 Jun;33(6):411-7
Levine M, et al. Complications following antidotal use of intravenous lipid emulsion therapy. J Med Toxicol. 2014 Mar;10(1):10-4.
Tian H, et al. Safety and efficacy of a new parenteral lipid emulsion (SMOF) for surgical patients: a systematic review and meta-analysis of randomized controlled trials. Nutr Rev. 2013 Dec;71(12):815-21.
Groszek B. [Intravenous fat emulsions in toxicology]. [Article in Polish] Przegl Lek. 2012;69(8):477-82.
Mercado P, Weinberg GL. Local anesthetic systemic toxicity: prevention and treatment. Anesthesiol Clin. 2011 Jun;29(2):233-4
Ciechanowicz S, Patil V. Lipid emulsion for local anesthetic systemic toxicity. Anesthesiol Res Pract. 2012;2012:131784. Epub 2011 Sep 29
Fernandez, A et al. The use of intravenous lipid emulsion as an antidote in veterinary toxicology. J Vet Emerg Crit Care. 2011 June 3.
Cave G, Harvey M, Graudins A. Intravenous lipid emulsion as antidote: a summary of published human experience. Emerg Med Australas. 2011 Apr;23(2):123-41
Bern S, Weinberg G. Local anesthetic toxicity and lipid resuscitation in pregnancy. Curr Opin Anaesthesiol. 2011 Apr 13.
Bern S, et al. Lipid resuscitation: a life-saving antidote for local anesthetic toxicity. Curr Pharm Biotechnol. 2011 Feb 1;12(2):313-9.
Skjønnemand M, et al. [Intravenous administration of lipids in poisoning caused by local analgesics] [Article in Danish] Ugeskr Laeger. 2011 Jan 10;173(2):120-3.
Toledo P. The role of lipid emulsion during advanced cardiac life support for local anesthetic toxicity.J Obstet Anesth. 2011 Jan;20(1):60-3. Epub 2010 Nov 26.
Burch MS, et al. Treatment of local-anesthetic toxicity with lipid emulsion therapy. Am J Health Syst Pharm. 2011 Jan 15;68(2):125-9.
Sandlin-Leming DC. Resuscitation of local anesthesia-induced cardiac arrest: lipids to the rescue. J Perianesth Nurs. 2010 Dec;25(6):418-20.
Lui KC, Chow YF. Safe use of local anaesthetics: prevention and management of systemic toxicity. Hong Kong Med J. 2010 Dec;16(6):470-5
Rothschild L, et al. Intravenous lipid emulsion in clinical toxicology. Scand J Trauma Resusc Emerg Med. 2010 Oct 5;18:51.
Dillane D, Finucane BT.Local anesthetic systemic toxicity. Can J Anaesth. 2010 Apr;57(4):368-80
Bourne E, Wright C, Royse C. A review of local anesthetic cardiotoxicity and treatment with lipid emulsion. Local and Regional Anesthesia. Feb 2010:3 11-19
Jamaty C, et al. Lipid emulsions in the treatment of acute poisoning: a systematic review of human and animal studies. Clin Toxicol (Phila). 2010 Jan;48(1):1-27.
Leskiw U, Weinberg GL.Lipid resuscitation for local anesthetic toxicity: is it really lifesaving? Curr Opin Anaesthesiol. 2009 Oct;22(5):667-71
Cave G, Harvey M. Intravenous lipid emulsion as antidote beyond local anesthetic toxicity: a systematic review. Anesthesiology. 2009 Sep;111(3):498-505.
Weinberg, G. Lipid Rescue Resuscitation from Local Anaesthetic Cardiac Toxicity. Toxicological Reviews, Volume 25, Number 3, 2006, pp. 139-145(7)
Guy L Weinberg, Malek G Massad, Metabolic modulation for cardiac protection.Expert Review of Cardiovascular Therapy, March 2007, Vol. 5, No. 2, Pages 135-138
Malinovsky JM, et al. Le Comité douleur-anesthésie locorégionale de Sfar. [Systemic toxicity of local anaesthetics and lipid emulsions: an interesting supplementary alternative]. Ann Fr Anesth Reanim. 2008 Feb;27(2):132-4
Copyright © 2012, Guy Weinberg, MD. All rights reserved.